William Keye, MD
Director, Division of Reproductive Endocrinology and IVF Programs
Department of Obstetrics and Gynecology
William Beaumont Hospital
3535 West Thirteen Mile Road, Suite 344
Royal Oak, Michigan 48073
Office Telephone Number: (248) 551-0515
E-mail: wkeye@beaumont.edu
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Education
- Undergraduate: Carleton College, Northfield, Minnesota, 1961-1963
- B.A.: University of Minnesota, Minneapolis, Minnesota, 1963-1965 (magnum cum laude)
- M.D.: University of Minnesota, Minneapolis, Minnesota, 1965-1969
- Internship: Department of Internal Medicine, University of Minnesota, Minneapolis, Minnesota, 1969-1970
- Residency: Department of Obstetrics and Gynecology, University of California, San Francisco, California
1973 (July-December), 1977 (January-June)
- Fellowship: Department of Obstetrics and Gynecology,
Reproductive Endocrinology Program.
University of Michigan, Ann Arbor, Michigan, 1972-1973, Directed by Robert B. Jaffe,
M.D.
- Department of Obstetrics and Gynecology, Reproductive Endocrinology Program,
University of California, San Francisco, California, 1974 (January - June) and 1976 (July - December), Directed by Robert B. Jaffe,
M.D.
Certification
- Board Certification: Obstetrics and Gynecology, 1981; Recertified 2000
- Reproductive Endocrinology, 1982; Recertified 2000
Professional experience
- Military: Department of Obstetrics and Gynecology,
Barksdale AFB, Bossier City, Louisiana, 1974-1976
- Private Practice: Physician, Student Health Service,
Centenary College, Shreveport, Louisiana, 1974-1976
- Department of Obstetrics and Gynecology,
Caylor-Nickel Clinic, Bluffton, Indiana, July 1977 - December 1979
Licensure
Academic appointments
- Assistant Professor,
Department of Obstetrics and Gynecology, University of Utah College of Medicine,
December 1979 - 1984
- Associate Professor, Department of Obstetrics and Gynecology,
University of Utah, College of Medicine, 1984 - 1990
- Chief, Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology,
University of Utah College of Medicine, 1983 - 1990
- Director, Division of Reproductive Endocrinology and Infertility and IVF Program,
Department of Obstetrics and Gynecology, William Beaumont Hospital, Royal Oak, Michigan,
1990 - Present
- Associate Clinical Professor,
Department of Obstetrics and Gynecology, University of Michigan, 1992 - present
Professional organizations
- American Association of Gynecologic Laparoscopists,
Member 1983-1985 1997-present
- American Association of Sex Educators, Counselors and Therapists,
Member 1980-1984
- American College of Obstetricians and Gynecologists
- Fellow 1982 - Present
- Audio-Visual Education Committee
- Member 1991-1994
- Chairman, 1994
- American Society for Psychosomatic Obstetrics and Gynecology,
Member 1982 - 1990
- American Society for Reproductive Medicine (formerly American Fertility Society)
- Member 1978 - present
- Society Development Committee 1985-1989
- Movie Selections Committee 1987
- Annual Program Committee Member 1989-1991
- Chairman 1991
- Board of Directors 1995-1997, 1999-2004
- Ethics Committee 2004
- Finance Committee
- Member 1995-1996
- Chairman 1997
- Executive Committee 1997,1999-2004
- Nominating Committee 1999-2004
- Program Policy Committee, 2000-2004
- Vice-President, 1999-2000
- President Elect 2000-2001
- President 2001-2002
- American Medical Association,
Member,1980 - 2002
- Central Association of Obstetricians and Gynecologists
- Member,1982 - 2003
- Planning Committee,1988
- European Society of Human Reproduction and
Embryology, Member,1999-present
- Gynecologic Laser Society
- Member,1983 - 1990
- Nominating Committee,1988
- Credentials Committee,1989
- Board of Directors,1985-1987
- Gynecologic Surgery Society,
Board of Directors,1996-1997
- International Society for Gynecologic Endoscopy
- Founding member,1988
- Grants Committee,1988
- Board of Directors,1988 - 1992
- Michigan Society of Reproductive Endocrinologists
- Member,1991 - present
- President,1994 –1995
- Pacific Coast Fertility Society
- Member,1980 - present
- Chairman Hospitality Committee,1985
- Director of CME,1984 - 1989
- Chairman Grants Committee,1987
- Program Chairman for Annual Meeting,1989
- Board of Directors,1989 - 1991
- Society for Lasers in Medicine and Surgery
- Member,1983 - 1988
- Chairman, Professional Liaison Committee,1984
- Salt Lake County Medical Society,
Member,1979 - 1990
- Society of Assisted Reproductive Technologies,
Member,1983 - present
- Society of Reproductive Endocrinology and Infertility,
Charter Member,1983 - Present
- Society of Reproductive Surgeons
- Charter Member,1985 - present
- Treasurer,1991
- Secretary,1992
- Vice President,1993
- President,1994
- Executive Committee ,1991 - 1997
- Chairman, Fellowship Committee,1996 - 2002
- AAGL Dialogue Committee Chair,1999-2000
- Utah State Medical Association,
Member,1979 - 1990
- Utah State Obstetrics and Gynecology Society,
Member,1979 - 1990
- Awards/Honors National Science Foundation Undergraduate Research Fellowship,1986
- ACOG - Ortho Academic Training Fellowship1972 - 1973
- ACOG - Purdue Frederick Award for Medical Research, 1975
- AFD - ACOG Chairman's Award for Clinical Research, 1975
- Ephraim McDowell Prize for Clinical Research, presented at the annual District V Meeting of ACOG,1977
- Prize Award, Central Association of Obstetrics and Gynecology,1978
- ACOG - Purdue Frederick Award for Medical Research,1978
- Indiana Obstetric and Gynecologic Society Award for Scientific Research,1979
- CSL - Serono Lectureship, The Fertility Society of Australia,1986
- Organon Lectureship, Australian Society for the Psychosomatic Aspects of Reproductive Medicine,1987
- Honorary Member, Australian Society for the Psychosomatic Aspects of Reproductive Medicine ,1987
- Chief Resident's Training Award, University of Utah 1988
- Listed in Town and Country's Directory of Outstanding Medical Specialists in the United States. November, 1989
- Dalton Society Medal, 1990
- Listed in The Best Doctors in America, 1993-2003
- Listed in Marquis Who's Who in Science and Engineering, 1995
- Listed in The Top Docs, Detroit Monthly Magazine
1995, 1996
- Listed in Marquis Who's Who in Medicine and Healthcare, 1995, 1997
- Listed in The Best Doctors in Metro Detroit,
Detroit Free Press, 1996
- Listed in The Best Doctors in America: Midwest Region, 1996-1997
- Listed in Positive Physician Honor Role,
The 50 Most Positive Doctors in America, 1996 Spencer Books Ltd, Phil.
- Listed in The Best Doctors for Women, Good Housekeeping, August, 1997
- Listed in Women’s Health Style,
Top 10 Doctors for Women in Detroit, 1999
- Speaking of Women’s Health and Detroit Public
Television Honoree for work on behalf of the health and well-being of
women, 2000
- Morton and Diane Stenchever Lecturer at the Annual Clinical Meeting of ACOG, San Francisco, May 25, 2000
- Listed in Best Doctors, 2001-2002
- Listed in Who’s Who in American Education, 2003
- Pioneer In Reproductive Medicine Award
Pacific Coast Reproductive Society, 2003
Research interest
- Development of Lasers for Gynecologic Surgery
- Photodynamic Therapy of Endometriosis
- Emotional Impact of Infertility
- Hormone Therapy in the Menopause
- Ovulation Induction for In Vitro Fertilization
- Etiology and Pathophysiology of Premenstrual Syndrome
- Patient-Physician Interpersonal Communications
- Medical Economics of Infertility
Grants
- University of Utah Faculty Research Grant, l98l, Principal Investigator.
Title: Development of the Utah Infertility Reactions Scales (UFIRS), 1983
- Co-Principal Investigator.
Title: Free Electron Laser Research Grant, Office of Naval Research (Dr. John Dixon, PI), 1986
- William Beaumont Hospital Research Institute Grant,
Co-Investigator
Title: A Double-Blind, Randomized, Parallel, Placebo-Controlled Study to Determine the Efficacy and Safety of the Synthetic Progestin Nomegestrol Acetate in the Treatment of Oligomenorrhea and Secondary Infertility, 1995
- William Beaumont Hospital Research Institute,
Co-Investigator
A Randomized, Double-Blind, Placebo and Active-Controlled, Parallel, Multi-center Study To Assess The Safety and Efficacy of 3 2-Day Combinations of 17β-Estradiol/Norethindrone Acetate Transdermal Delivery Systems For Relief of Menopausal Vasomotor Symptoms and Reduction of Endometrial Hyperplasia.
(Dr. Charles Lucas, PI), 1997
- William Beaumont Hospital Research Institute,
Principal Investigator
Title: A Randomized Open-Label, Parallel Group Multi-Center, Efficacy Study Comparing Repronex S.C., Repronex I.M., and Pergonal I.M. In Female Patients Undergoing In Vitro Fertilization,
Sponsored by Ferring Pharmaceuticals Inc., 1997
- William Beaumont Hospital Research Institute,
Principal Investigator
Title: A Phase III, Multi-center, Multinational, Randomized, Assessor-Blind Study To Compare The Safety and Efficacy of New Formulation of Recombinant Human FSH (r-hFSH) Versus Fertinex versus Gonal F In Stimulating Multiple Follicular Development Prior to ART in Patients Pretreated with GnRH Agonist, 2000,
Sponsored by Serono, Inc
- William Beaumont Hospital Research Institute,
Principal Investigator
Title: A Randomized, Comparative, 3-ARM, Parallel Group, Open-Label, Multi-center Study of the Efficacy and Safety of Purified Human FSH
(hFSH) SC and Repronex® SC When Combined in Continuous or Sequential Dose Ratios in Female Patients 34-40 Years of Age, Undergoing In-Vitro Fertilization (IVF), 2001,
Sponsored by Ferring Pharmaceuticals, Inc
- William Beaumont Hospital Research Institute,
Principal Investigator
Title: A Randomized Quality of Life, Efficacy, Safety and Tolerability (QUEST) Study of Bravelle+Repronex vs. Gonal-F in Controlled Ovarian Hyperstimulation for In Vitro Fertilization, 2003,
Sponsored by Ferring Pharmaceuticals
- Serono Symposia, Investigator
Validation of the Ferti-QOL Questionnaire
Academic committees
- Subcommittee on Scientific Exhibits,
Tenth World Congress of Gynecology and Obstetrics, October 17-22, 1982
- Gender Identity Committee,
University of Utah Medical Center, 1979 - 1990
- Quality Assurance Committee,
University of Utah Medical Center, 1980
- Outpatient Surgery Advisory Committee,
University of Utah Medical Center, 1982 - 1986
- Search Committee for Chairman,
Family and Community Medicine, University of Utah, 1982 - 1983
- Outpatient Surgery Committee,
Department of Obstetrics and Gynecology, University of Utah, 1983 - 1990
- Accreditation Committee for Continuing Medical Education,
University of Utah, 1986
- Ambulatory Surgery Committee, University of Utah Health Sciences Center,
1984 – 1990
- Chairman, Physician's Advisory Committee,
University of Utah Laser Institute, 1987 - 1990
- Endoscopy Committee, William Beaumont Hospital,
1991 – 1994
- Search Committee for Chairman,
Department of Obstetrics and Gynecology, William Beaumont Hospital, 2003-2004
Editorial experience
- Books:
- Keye WR, Jr (guest editor): Clinics in Obstetrics and Gynecology; Female Sexuality. Harper and Row, Philadelphia, Pennsylvania, 1984
- Lockey J, Lemasters G, Keye WR, Jr (editors): Reproduction: The New Frontier in Occupational and Environmental Health Research. Alan & Liss, Inc., New York, 1984 Michigan, 1984
- Keye WR, Jr (editor): Lasers in Obstetrics and Gynecology, GK Hall, Boston, Massachusetts, 1985
- Keye WR, Jr (editor): Premenstrual Syndrome. WB Saunders, Philadelphia, 1988
- Keye WR, Jr (editor): Lasers in Gynecology and Obstetrics, Yearbook Publishers, Chicago, 1990
- Keye WR, Jr, Chang JR, Rebar R, Soules MR (editors): Infertility: Evaluation and Treatment. W.B. Saunders, Philadelphia, Pennsylvania, 1995
- Keye WR, Jr. (guest editor): Contemporary Management of Infertility in Clinical Obstetrics and Gynecology. Lippincott Williams & Wilkins, 2000
- Journals:
- Reviewer, Fertility and Sterility
- Reviewer, Obstetrics and Gynecology
- Reviewer, International Journal of Gynecology and Obstetrics
- Reviewer, Journal of Gynecologic Surgery
- Reviewer, Gynaecological Endoscopy
- Reviewer, Journal of Women's Health
- Editorial Board, Journal of Gynecologic Surgery
- Editorial Board, Gynaecological Endoscopy
- Ad Hoc Review Committee, Journal of the American Association of Gynecologic Laparoscopists
Community activities
- RESOLVE, INC, Medical Advisor, Indiana Resolve 1979
- Co-Founder, Resolve of Utah 1980
- President, Resolve of Utah 1980 - 1981
- Medical Advisor 1980 – 1990
- Member, Physician's Advisory Group, National RESOLVE 1985 - 1997
- Medical Advisory Board, Planned Parenthood of Utah, 1981 – 1982
- Medical Advisor, Utah Chapter of the National PMS Society 1982- 1987
- Chairman of the Medical Advisory Board of the Utah PMS Center 1983 - 1988
- Member, Advisory Board of Directors, Park City Family Counseling Institute 1982 - 1987
- University of Utah Golf Open,
Planning Committee, 1983, 1984, 1985, 1986
- User Committee, University of Utah Medical Center,
1982 - 1983
- Volunteer radio announcer and moderator of "Health Talk", a weekly health program on KPCW, a volunteer radio station in Park City, Utah, January, 1981 - January 1983
- Director, The Annual Utah Women's Health Golf Open (a fundraiser for the research fund of the Department of Obstetrics and Gynecology, University of Utah), 1986-1989
- William Beaumont Hospital Speakers Bureau, 1990 - Present
- Director, Women's Advisory Committee, William Beaumont Hospital, 1991 - Present
- Planning Committee, Annual Womens’ Health Day,
William Beaumont Hospital, 1996-2000
- Faculty, University of Life,
First United Methodist Church, Birmingham, Michigan 1997
TEACHING RESPONSIBILITIES/ASSIGNMENTS
- Courses Lecturer, Organ System Course in Obstetrics and Gynecology, University of Utah 1980 - 1990
- Lecturer, Clerkship in Obstetrics and Gynecology, 1980 - present
- Lecturer, summer school on alcohol and other drug dependencies, University of Utah, 1983, 1984
- Program Chairman, Symposium on Medicine and Biology, ICALEO Meeting, Sponsored by the Laser Institute of America, 1984
- International Advisory Board, The Second International Symposium on Premenstrual, Postpartum, and Menopausal Mood Disorders, 1985 – 1987
- Organizing Committee for the Second International Symposium on Premenstrual, Postpartum and Menopausal Mood Disorders,
1985 - 1987
- Lecturer, Obstetrics and Gynecology Grand Rounds, William Beaumont Hospital,
1990 - Present
- Lecturer, Resident Conferences,
William Beaumont Hospital, 1990 - Present
- Faculty, The International Society for Gynecologic Endoscopy - Medcom Management International, Inc.,
1990 - 1992
- Visiting Professor, Monash University,
Melbourne, Australia, February, 1991
- Contributor to Written Examination in Reproductive Endocrinology,
The American Board of Obstetrics and Gynecology, 1991
- Preceptor at the Bronson Laser Institute,
Bronson Methodist Hospital, Kalamazoo, Michigan, November 30, 1990, January 25 and February 22, 1991
- Lecturer, All Michigan Ob/Gyn Review Course,
1992 - 1999
- Faculty, OHEP - Wayne State University Laser Endoscopy Courses,
1992 - 1995
- Faculty, MMI Risk Management Resources, Inc.,
1992 - 1998
- Faculty, Advanced Practicum in Gynecologic Operative Laparoscopy, William Beaumont Hospital,
1992 - Present
- Lecturer, OHEP Postgraduate Course in Obstetrics and Gynecology,
1993 - 1999
Student Supervision
- Committee Member, Master's Candidate, Sue Butell, College of Nursing, University of Utah, 1980
- Committee Member, Master's Candidate, Thad Wilson, College of Nursing, University of Utah, 1981
- Committee Member, Ph.D. Candidate, Stacey Levine, College of Nursing, University of Utah, 1984
- Committee Member, Ph.D. Candidate, Ann Deneris,
Health Education, University of Utah, 1985
- Committee Member, Ph.D. Candidate, Eric Trunnell, Health Education University of Utah, 1986
- Committee Member, Master's Candidate Stephanie Zimmer, College of Nursing, University of Utah, 1987
- Committee Member, Ph.D. Candidate, Carol Wilson-Larsen, Health Education, University of Utah, 1987
- Honors Student in Obstetrics and Gynecology, 1981 Research Project: The Development of the Argon Laser as Therapy for Endometriosis
- Honors Student in Obstetrics and Gynecology, 1982 Research Project: Premenstrual Syndrome
- Honors Student in Obstetrics and Gynecology, 1983 Research Project: Evaluation of the High Energy Argon Laser
- Honors Student in Obstetrics and Gynecology, 1985 Research Project: SHBG Concentrations in Women with Premenstrual Syndrome
- Honors Student in Obstetrics and Gynecology, 1985 Research Project: The Application of Lasers to the Treatment of Infertility
- Honors Student in Obstetrics and Gynecology, 1986 Research Project: Psychological Profile of Women with Premenstrual Symptoms
- Honors Student in Obstetrics and Gynecology, 1986 Research Project: Creation of Limb Reduction Defects in the Chick Embryo with the Argon and Copper Lasers
- Honors Student in Obstetrics and Gynecology, 1986 Research Project: Histologic Changes Associated with the Sapphire Contact Probe Coupled to the Argon and YAG Lasers
- New Courses Developed: Coordinator of a Multidisciplinary Conference on Reproductive Endocrinology and Infertility, 1981 - 1984
- Course Director, Infertility Laser Surgery, Co-sponsored by The American Fertility Society and the Laser Institute of the University of Utah, 1985
- Course Co-Director, 1985 AFS Postgraduate Course, Reproductive Medicine and Infertility for Nurses, 1985
- Course Director, Infertility Laser Surgery, co-sponsored by The American Fertility Society and the Laser Institute of the University of Utah, March 15-16, 1985, September 6-7, 1985, January 17-18, 1986, March 28-29, 1986, September 18-19, 1986
- Course Co-Director, 1986 AFS Postgraduate Course: Reproductive Medicine and Infertility for Nurses, September 1986, Toronto
- Course Director, 1987 AFS Postgraduate Course: Controversies in Reproductive Medicine,
May 1987, Orlando
- Course Director, 1988, University of Utah Department of Obstetrics and Gynecology Annual Postgraduate Subspecialty Course, Update in Reproductive Endocrinology and Infertility,
February 1988, Park City, Utah
- Program Director, Managing the Menopause in the 1990's Symposium,
William Beaumont Hospital, Royal Oak, Michigan, April 27, 1991
- Program Director, Clinical Use of GnRH-Agonists, William Beaumont Hospital, Royal Oak, Michigan, September 7, 1991
- Course Director, Postgraduate Course for The American Fertility Society on Critiques of New Reproductive Surgeries, Marina Del Ray, California,
November 21 - 23, 1991
- Course Director, Management of Ovulation Disorders in Infertile Women, William Beaumont Hospital
February 15, 1992
- Course Director, Postgraduate Course for The American Fertility Society on Reproductive Medicine, Bermuda, May, 1992
- Course Director, Postgraduate Course for The American Fertility Society, Gadgets, Gidgets and Gambits for the Office and Operating Room,
November, 1994
- Course Director, Postgraduate Course for ACOG on Operative Laparoscopy. Rancho Mirage, California, January 26 - 28, 1995
- Course Director, Postgraduate Course for The American Society for Reproductive Medicine, Infertility: Turning Science Into Clinical Care, San Francisco, California, October, 1998
Consultant
- Women's Care Corporation, 1983 - 1988
- Abbott-Northwestern Hospital Women's Center, Minneapolis, Minnesota, 1984
- Utah Valley Hospital PMS Center, Provo, Utah, 1985
- Community Hospital Laser Surgery Program, Missoula, Montana, 1987
- Abbott-Northwestern Hospital Laser Surgery Program, Minneapolis, Minnesota, 1987
- Allen Memorial Hospital Women's Center, Waterloo, Iowa, 1987
- Bayview Hospital, Corpus Christi, Texas, 1987
- St. Benedict's Hospital PMS Center, Ogden, Utah,
1985 - 1986
- Sister Francis Hospital, Tyler, Texas, 1988
- Rose Memorial Medical Center, Denver, Colorado, 1988
- Outpatient Surgi-Center, Bozeman, Montana, 1988
- Bronson Hospital, Kalamazoo, Michigan Laser Preceptor, 1991
- Ferring Pharmaceuticals, Inc., Member, Physicians Advisory Board, 1997 - Present
- Organon Pharmaceuticals, Member, Physicians Advisory Board, 1997 - 2000
Bibliography
Scientific Publications
- Keye WR, Jr, Kelch RP, Niswender GD, Jaffe, RB: Quantitation of endogenous and exogenous gonadotropin releasing hormone by radioimmunoassay. J Clin Metab 36:1263, 1973
- Jaffe RB, Ho Yuen B, Keye WR, Jr, Midgley AR, Jr: Physiologic and pathologic profiles of circulating human prolactin. Am J Obstet Gynecol 117:757, 1973
- Keye WR, Jr, Jaffe RB: Modulation of gonadotropin response to gonadotropin releasing hormone by estradiol. J Clin Endocrinol Metab 38:805, 1974
- Jaffe RB, Keye WR, Jr: Estradiol augmentation of pituitary responsiveness to gonadotropin releasing hormone in women. J Clin Endocrinol Metab 39:850, 1974
- Keye WR, Jr, Jaffe RB: Strength characteristics of estrogen effects on gonadotropin response to gonadotropin releasing hormone in women. J Clin Endocrinol Metab 41:1003, 1975
- Jaffe RB, Keye WR, Jr: Modulation of pituitary response to hypothalamic releasing factors. J Steroid Biochem 67:1055, 1975
- Keye WR, Jr, Jaffe RB: Changing patterns of LH and FSH responses to gonadotropin releasing hormone in the puerperium. J Clin Endocrinol Metab 2:1133, 1976
- Keye WR, Jr, Ho Yuen B, Knopf RF, Jaffe RB: Amenorrhea, hyperprolactinemia and pituitary enlargement secondary to primary hypothyroidism: Successful treatment with thyroid replacement. Obstet Gynecol 48:697-702, 1976
- Chang RJ, Keye WR, Jr, Young JR, Wilson CB, Jaffe RB: Detection, evaluation and treatment of pituitary microadenomas in patients with galactorrhea and amenorrhea. Am J Obstet Gynecol 128:356-363, 1977
- Keye WR, Jr, Chang RJ, Monroe S, Wilson CB, Jaffe RB: Prolactin secreting pituitary adenomas in women. II. Menstrual function, pituitary reserves, and prolactin production following microsurgical removal. Am J Obstet Gynecol 134:360-365, 1979
- Keye WR, Jr, Chang RJ, Wilson CB, Jaffe RB: Prolactin secreting adenomas in women: III. Frequency and diagnosis in amenorrhea-galactorrhea. JAMA 244:1329-1332, 1980
- Chang, RJ, Keye WR, Monroe, SE, Jaffe RB: Prolactin secreting pituitary adenomas in women. IV. Pituitary function in amenorrhea associated with normal or abnormal serum prolactin and sellar polytomography. J Clin Endocrinol Metab 51:830-833, 1980
- Monroe, SE, Levine L, Keye WR, Jr, Chang RJ, Jaffe RB: Prolactin secreting adenomas in women. V. Increased gonadotrophin sensitivity in hyperprolactinemic women with pituitary adenomas. J Clin Endocrinol Metab 52:1171, 1981
- Scott JR, Keye WR, Jr, Poulson AM, Reynolds WA: Ovarian transplantation in the primate. Fertil Steril 36:512, 1981
- Bader PI, Keye WR, Jr, Cowan J: Mullerian Agenesis, hypoplasia of distal extremities, unusual dermatoglyphics and pigmentation. Obstet Gynecol 60:263, 1982
- Keye WR, Jr, Matson GA, Dixon J: The use of the argon laser in the treatment of experimental endometriosis. Fertil Steril 39:26, 1983
- Keye WR, Jr, Dixon J: Photocoagulation of endometriosis by the argon laser through the laparoscope. Obstet Gynecol 62:383, 1983
- Hammond DC, Keye WR, Jr, Grant CW, Jr: Hypnotic analgesia with burns: An initial study. J Clin Hypnosis 26:56, 1983
- Keye WR, Jr, Deneris A: Female sexual activity, satisfaction and function in infertile women. Infertility 5:275, 1983
- Keye WR, Jr, Poulson AM, Worley RJ: Application of simplified laser laparoscopy to preparation of the pelvis for in vitro fertilization. J Reprod Med 30(5):418-20, 1985
- Keye WR, Jr, Hammond DC, Strong T: Medical and psychological characteristics of women presenting with premenstrual syndrome. Obstet Gynecol 68(5):634-7, 1986
- Keye WR, Jr, Trunnell EP: A biopsychosocial model of premenstrual syndrome. International Journal of Fertility 31(4):259-62, 1986
- Keye WR, Jr, Hansen LW, Astin M, Poulson AM, Jr: Argon laser therapy of endometriosis: a review of 92 consecutive patients. Fertil Steril 47(2):208-12, 1987
- Trunnell EP, Turner CW, Keye WR, Jr: A comparison of the psychological and hormonal factors in women with and without premenstrual syndrome. J Abn Psych 97:429-436, 1988
- Urry RL, Middleton RG, Jones KP, Poulson AM, Worley RJ, Keye WR, Jr: Artificial insemination: A comparison of pregnancy rates with intrauterine versus cervical insemination and washed sperm versus serum swim-up sperm preparations. Fertility and Sterility 49:1036-38, 1988
- Keye WR Jr: Premenstrual syndrome. Seven steps in management. Postgraduate Medicine 83(3):167-73, 1988
- Wilson CA, Keye WR, Jr: A survery of adolescent dysmenorrhea and premenstrual symptom frequency. A model program for prevention, detection and treatment. J Adolescent Health Care 10(4):317-22, 1989
- Wilson CA, Keye Wr, Jr, Abdenour TE: Menstrual Disorders Among Intercollegiate Athletes and Non-Athletes: Perceived Impact on Performance. Athletic Training, JNATA, 26, 1991
- DeLia JE, Cruikshank DP, Keye WR, Jr: Fetoscopic neodymium:YAG laser occlusion of placental vessels in severe twin transfusion syndrome. Obstet Gynecol 75(6):1046-53, 1990
- Keye WR Jr: Laser surgery and adhesion formation. Progress in Clinical & Biological Research 358:67-76, 1990
- Petrucco OM, Sathananden M, Knowles S, McKenzie L, Forbes IJ, Cowled PM, Keye WR, Jr: Ablation of endometriotic implants in rabbits by haematoporphyrin derivative photoradiation therapy using the gold vapour laser. Lasers in Med and Surgery; 10( 4):344-8, 1990
- Wilson CA, Turner CW, Keye WR, Jr: Mothers and firstborn adolescent daughters with and without premenstrual syndrome: a comparison. Journal of Adolescent Health; 12(2):130-7, 1991
- Hales HA, Peterson CM, Jolles CJ, Varner MW, Keye WR: Pseudomyxoma peritonei associated with secondary infertility. Fertility and Sterility 58(2):425-6, 1992
- Keye WR Jr: Hitting a moving target: credentialing the endoscopic surgeon. Fertility and Sterility 62(6):1115-17,1994
- Keye WR Jr: Laparoscopy in the 1990's: deja vu all over again. Fertility and Sterility
66(4):511-512,1996
- Gocial B, Keye WR, Fein S, Nardi R, Repronex SC, IVF Study Group: Subcutaneously
administered Repronex in female patients undergoing in vitro fertilization is as effective and well tolerated as intramuscular menotropin treatment. Fertility and Sterility 74(1):73-79,2000
- Keye WR Jr., Marrs RP, Check JH, Schnell V, Surrey, Marshall DC: Evaluation of Mixed Protocols with Bravelle(hFSH) and Repronex(hMG) to Assess Their Clinical Efficacy(EMBRACE) in Subjects Undergoing In Vitro Fertilization. Fertility and Sterility (Accepted for Publication)
- Keye, WR Jr., Bradshaw KD: A Survey of the Practices and Opinions of the Domestic Members of the American Society for Reproductive Medicine. Fertility and Sterility (Accepted for Publication)
- Keye WR Jr. ASRM: Reaching Its Full Potential. Fertility and Sterility (Accepted for Publication)
- Hatoum HT, Keye WR, Marrs RP, Walton SM: A Markov Model of the Cost Effectiveness of Human-Derived FSH vs Follistim-beta Using Comparative Clinical Trial Data Fertility and Sterility (Submitted)
Reviews
- Ho Yuen B, Keye WR, Jr, Jaffe RB: Human prolactin: Secretion, regulation and pathophysiology. Obstet Gynecol Survey 28:526, 1973
- Keye Wr, Jr, Ho Yuen B, Jaffe RB: New concepts in the physiology of the menstrual cycle. Clinics Endocrinol Metab 2:451, 1973
- Keye WR, Jr, Young JR, Jaffe RB: Hypothalamic gonadotropin releasing hormone: Physiologic and clinical considerations. Obstet Gynecol Survey 31:635-654, 1976
- Keye WR, Jr, Chang RJ, Jaffe RB: Prolactin secreting pituitary adenomas in women with disorders of menstruation and lactation. Obstet Gynecol Survey 32:727-738, 1977
- Keye WR, Jr: Avoiding iatrogenic infertility. Contemp Obstet Gynecol 19:185, 1982
- Keye WR, Jr: Evaluation and management of hirsutism. Med Aspects Human Sexuality 16:190, 1982
- Keye WR, Jr, Strong T: Premenstrual syndrome: An enigma. Continuing Education for the Family Physician, p 913, 1983
- Bank KM, Lockey JE, Keye WR, Jr: Reproductive hazards in the workplace. Fam Com Health 6:44, 1983
- Keye WR, Jr: Premenstrual syndrome. Endocrine and Fertility Forum 6:1, 1983
- Keye WR, Jr: Premenstrual syndrome. Contemp Ob/Gyn, April 1984
- Keye WR, Jr: Premenstrual syndrome: Fad, fact or fallacy. J Assoc Mormon Counselors and Psychotherapists, p 13, July 1983
- Keye WR, Jr, Dixon J: Photocoagulation of endometriosis by the argon laser. Med Instruments and Supplies 14:38, 1984
- Keye WR, Jr: Medical therapy of premenstrual syndrome. Canadian Psychiatric Journal 30(7):483-8, 1985
- Keye WR, Jr: Flexible wave guides for simplified laser laparoscopy. Proceedings of the l984 ICALEO Meeting of the Laser Institute of America, 1985
- Keye WR, Jr, Trunnel E: Premenstrual syndrome: A medical perspective. Hamline University Law Review, March 1986
- Keye WR, Jr: The present and future uses of lasers for the treatment of endometriosis. International Journal of Fertility 3l(2):160-4, 1986
- Keye WR, Jr, Matson GA, Dixon J: The use of the argon laser in the treatment of experimental endometriosis. Med Instruments and Supplies 18:31, 1986
- Blackwell RE, Carr BR, Chang RJ, DeCherney A, Haney AF, Keye WR, Jr, Rebar RW, Rock JA, Rosenwaks Z, Serbel M, Soules MR: Are we exploiting the infertile couple. Fert Steril 48(5):735-739, 1987
- Keye WR, Jr: Guiding infertile patients. Cont Obstet Gynecol 30:151, 1987
- Keye WR, Jr: General evaluation of premenstrual symptoms. Clin Obstet Gynecol 30(2):396-407, 1987
- Keye WR, Jr: Yes, PMS may all be in your head. Clin Obstet Gynecol 1(9):1, 1988
- Keye WR, Jr: The management of PMS. Postgrad Med 83:167, 1988
- Keye WR, Jr: Premenstrual symptoms: evaluation and treatment. Compreh Therapy, 14:(10)19-26, 1988
- Keye WR, Jr: Use of the argon laser in the treatment of endometriosis. In Ballweg ML (ed): Overcoming Endometriosis. Congdon and Weed Inc, New York, 1987. pp 70-71
- Keye WR, Jr: Premenstrual syndrome. Western J Med 149(6):765, 1988
- Keye WR, Jr: Laser therapy of endometriosis. Women's Wellness 2:2, 1988
- Keye WR, Jr: Premenstrual syndrome. In Precis IV. Published by the American College of Obstetricians and Gynecologists 1990, pp 17-21
- Trunnell EP, White GL, Pederson DM, Keye WR, Jr: Premenstrual syndrome: Biopsychosocial model offers alternative treatment approach. Physician Assistant 13:45, 1989
- Keye WR, McArthur G: The argon laser in gynecologic surgery. Medical Laser Buyer's Guide 2:104, 1989
- Keye WR, Jr: Laparoscopic treatment of endometriosis. Obstetrics & Gynecologcy Clinics of North America 16(1):157-66, 1989
- Endicott J, Johnson SR, Keye WR: Helping the patient with PMS. Patient Care 24(3):44-75, 1990
- Keye WR: Abnormal Uterine Bleeding. In Endocrine & Fertility Forum 24(4): December, 1991
- Keye WR Jr: Operative Laparoscopy. In Endocrine & Fertility Forum 25(4): December, 1992
- Keye WR Jr: Unexplained Infertility. In Endocrine & Fertility Forum 26(4):December, 1993
- Keye WR Jr, Johnston Patricia: The Adoption Alternative - The Infertility Medical Teams Role. In Endocrine & Fertility Forum 27(4): December, 1994
- Keye WR, Jr: Premenstrual Syndrome. In Endocrine & Fertility Forum 28(4): December 1995
- Keye WR Jr: Psychologic Relationships. Clinical Obstetrics and Gynecology 37(3):67180,1994
Chapters
- Jaffe RB, Keye WR, Jr, Young JR: The role of estradiol in modulating LH and FSH response to gonadotropin releasing hormone. In Labrie F, Meites J, Pelletier G (eds). Hypothalamus and Endocrine Function. Plenum Press, New York, 1976, p 211
- Keye WR, Jr, Jaffe RB: Hirsutism and dysfunctional uterine bleeding. In Glass RH (ed), Current Topics in Office Gynecology, Williams and Wilkins, Baltimore, 1976, pp 208-226
- Jaffe RB, Keye WR, Jr, Chang RJ: Steroid modulation of gonadotropins in women. Proceedings of the International Symposium on Endocrinology of the Ovary, 1978
- Jaffe RB, Keye WR, Jr, Chang RJ: Hormone secretion during the normal menstrual cycle. In Linfoot JA (ed), Proceedings of the International Symposium on Recent Advances in the Diagnosis and Treatment of Pituitary Tumors, 1978
- Keye WR, Jr: Control of pituitary response to GnRH. In Sciarra JJ (ed), Gynecology and Obstetrics, Volume 5, Reproductive Endocrinology, Infertility and Genetics, Chapter 8, 1981, pp 1-10
- Keye WR, Jr, Jaffe RB: Hirsutism and
dysfunctional uterine bleeding. In Glass RH (ed), Current Topics in Office Gynecology, 2nd Edition, Williams and Wilkins, Baltimore, 1981, pp 233-251
- Keye WR, Jr, Matson GA, Cummings CE, Dixon J: The use of the argon laser in the treatment of endometriosis. Proceedings of the Second International Congress on Gynecologic Laser Surgery, Montreal, May 1982
- Keye WR, Jr: Overview of female reproduction. In Lockey J, Lemasters G, Keye WR, Jr (eds), Reproduction: The New Frontier in Occupational and Environmental Health Research, Alan R. Liss, New York, 1984, pp 189-200
- Keye WR, Jr: Environmental exposure and altered menstrual function. In Lockey J, Lemasters G, Keye WR, Jr (eds), Reproduction, The New Frontier in Occupational and Environmental Health Research, Alan R. Liss, Inc., New York, 1984, pp 203-210
- Worley RJ, Keye WR, Jr: Reproductive performance in previously infertile couples. In Aiman J (ed), Infertility: Diagnosis and Treatment, Springer-Verlag, New York, 1984
- Keye WR, Jr: Laser therapy of endometriosis. In Keye WR, Jr (ed), Lasers in Obstetrics and Gynecology, GK Hall, Boston, Massachusetts, 1984, pp 135-145
- Keye WR, Jr: Emotional and sexual problems in infertile couples. In Clinics in Obstetrics and Gynecology: Female Sexuality. Harper and Rowe, Philadelphia, Pennsylvania 1984, pp 760-766
- Keye WR, Jr: Counseling in obstetrics and gynecology. In Danforth DN (ed), Obstetrics and Gynecology, 5th Ed. JB Lippincott Company, New York, 1986, p 173
- Keye WR, Jr: Endoscopic laser surgery in gynecology. In Dixon J (ed), Surgical Application of Lasers. Yearbook Publishers, 1987, pp 183-217
- Keye WR, Jr: General evaluation of premenstrual symptoms. In Johsnon SB (ed), Clinics in Obstetrics and Gynecology 30:396, 1987, JB Lippincott Co, Philadelphia
- Keye WR, Jr: The emotional reactions to infertility. In Burrows GD, Petrucco OM, Llewellyn-Jones D (ed): Psychosomatic Aspects of Reproductive Medicine and Family Planning. York Press Printing Ltd, Abbotsford, Australia, 1987, p 55
- Keye WR, Jr: A biopsychosocial model of PMS. In Burrows GD, Petrucco OM, Llewellyn-Jones D (ed): Psychosomatic Aspects of Reproductive Medicine and Family Planning. York Press Printing, Ltd, Abbotsford, Australia, 1987, p 33
- Keye WR, Jr: The decision-making process as applied to reproduction. In Burrows GD, Petrucco OM, Llewellyn-Jones D (ed): Psychosomatic Aspects of Reproductive Medicine and Family Planning. York Press Printing, Ltd, Abbotsford, Australia, 1987, p 140
- Keye Wr, Jr, Trunnell E: A biopsychosocial model of premenstrual syndrome. In Keye WR, Jr (ed), Premenstrual Syndrome. WB Saunders, Philadelphia, 1988
- Keye WR, Jr: The clinical management of premenstrual syndrome. In Keye WR, Jr (ed), Premenstrual Syndrome. WB Saunders, Philadelphia, 1988
- Keye WR, Jr: Laser surgery for infertility: Past, present and future. In Ng Charles (ed), Frontiers in Reproductive Endocrinology and Infertility. Kluwer Academic Publisher, Dordrecht, 1988, pp 43-50
- Keye WR, Jr: Dysfunctional uterine bleeding. In Glass RH (ed), Current Topics in Office Gynecology. Third Edition, Williams and Wilkins, Baltimore, 1988, pp 199-208
- Keye WR, Jr: Laparoscopic treatment of endometriosis. In Rock J (ed): Obstetrics and Gynecology Clinics of North America. Yearbook Publishers, Chicago, 1988, pp 157-166
- Keye WR, Jr: Laser-assisted conservative pelvic operations - laser operations contrasted with conventional operative techniques. In Soules MR (ed): Problems in Reproductive Endocrinology and Infertility. Elsevier, New York, 1989, p 271.
- Keye WR, Jr: Argon laser laparoscopy. In Keye W (ed): Lasers in Gynecology and Obstetrics. Yearbook Publishers, 1990
- Keye WR, J: Premenstrual Syndrome. In Visscher H (ed): Precis IV: An Update in Obstetrics and Gynecology. American College of Obstetricians and Gynecologists, 1990, pp 17-21.
- Keye WR, Jr: The future of lasers in gynecology? Photodynamic therapy of benign disease. In Tsakok PHM (ed) Proceedings of the First International Scientific Meeting, Royal College of Obstetricians and Gynaecologists. World Scientific, Singapore, 1990, pp 128-135.
- Keye WR, Jr: Argon laser laparoscopy. In McLaughlin D (ed): Lasers in Gynecology. Lippincott, Philadelphia, 1991, pp 215-224.
- Keye WR, Jr: Premenstrual Syndrome (PMS). In Rakel R (ed): Conn's Current Therapy 1991. W.B. Saunders, Philadelphia, 1991, pp 1000-1003.
- Keye WR, Jr: KTP and argon laser laparoscopy. In Dorsey J (ed): Obstetrics and Gynecology Clinics of North America. W.B. Saunders, Philadelphia, 1991, pp 605-611.
- Keye WR, Jr: The early diagnosis and conservative management of ectopic pregnancy. The Second & Third Post-Graduate Courses on Clinical Reproductive Endocrinology & Infertility: Proceedings Jakarta, June 1990. Excerpta Medica, 1991
- Keye WR, Jr: The future of lasers in obstetrics and gynecology. The Second and Third Post-Graduate Courses on Clinical Reproductive Endocrinology & Infertility: Proceedings Jakarta, June 1990. Excerpta Medica, 1991
- Keye WR, Jr: Laser laparoscopy and videolaparoscopy in reproductive surgery. The Second and Third Post-Graduate Courses on Clinical Reproductive Endocrinology & Infertility: Proceedings Jakarta, June 1990. Excerpta Medica, 1991
- Keye WR, Jr: The future of laser surgery. In Sutton C (ed): Lasers in Gynaecology. Chapman and Hall, London, 1992, pp 257-268.
- Keye WR, Jr: Argon laser laparoscopy. In Baggish M (ed): Laser Endoscopy. Elsevier, New York, 1994
- Keye WR, Jr: Future Developments. In Martin MD, Adamson GD (eds): An Atlas of Endoscopic Management of Gynecologic Disease. New York: Raven Press, 1996, pp 76-81
- Keye WR, Jr: Premenstrual Syndrome. In Schlaff W (ed): Decision Making in Reproductive Endocrinology. Blackwell Scientific Publications, Oxford, England, 1993, pp 74-83
- Keye WR, Jr: Photodynamic Therapy. In Sutton C, Diamond M (eds): Endoscopic Surgery for Gynaecologists. W.B. Saunders, London, 1993, pp 387-392
- Keye WR, Jr: Premenstrual Syndrome (PMS). In Rakel R (ed): Conn's Current Therapy 1993. W.B. Saunders, Philadelphia, 1993, pp 1058-1062
- Keye WR, Jr: The Future of Reconstructive Pelvic Surgery. In Johns DA (ed): Infertility and Reproductive Medicine Clinics of North America. W.B. Saunders, Philadelphia, 1993, pp 415-426.
- Keye WR, Jr: Future Developments. In Martin MD, Adamson GD (eds): An Atlas of Endoscopic Management of Endoscopic Disease. Raven Press, New York, 1996, pp 421-427.
- Keye WR, Jr: The Initial Approach To The Infertile Couple. In Keye WR, Chang J, Rebar R, Soules M (eds): Infertility: Evaluation and Treatment. W.B. Saunders, 1995, pp 76-81
- Keye WR, Jr: Psychological Issues of Infertility. In Sciarra JJ (ed): Gynecology and Obstetrics, J.B. Lippincott Company, 1995;6 (Chap. 74)
- Keye WR, Jr: Female Infertility. In Diokno A, Jafri Z (eds): Lower Genitourinary Radiology, Diagnostic and Therapeutic. Springer-Verlag, New York, 1998
- Keye WR, Jr: Hormonal Approaches to Treatment of Mood Disorders. In Infertility and Reproductive Clinics of North American. W.B. Saunders, Philadelphia, 7(2): April 1996
- Keye WR, Jr, Johnston PI: Long-Term Effects of Infertility. In Adoptive Families. July/August, 1995, pp 8-12
- Keye WR, Jr. Premenstrual Syndrome. In Holzman GB, Rinehart RD, Moghissi KS (eds): PRECIS VI: An Update in Obstetrics and Gynecology. American College of Obstetricians and Gynecologists, 1998, pp 51-54
- Keye WR, Jr. Premenstrual Syndrome. In Fraser I, Jansen, R, Lobo, R. Whitehead M (eds): Estrogens and Progestogens in Clinical Practice. Churchill Livingstone, London 1998, pp 387-403
- Keye WR, Jr. Medical Aspects of Infertility for the Counselor. In Burns LH, Covington SN (eds): Infertility Counseling: A Comprehensive Handbook for Clinicians. Parthenon Publishing, New York, pp 27-46, 1998
- Keye WR, Jr., N. Edward Dourron. Cost-Effective Approach to the Evaluation and Management of the Couple with Unexplained Infertility. In Surrey MWS (ed): Infertility and Reproductive Medicine Clinics of North America. W.B. Saunders, Philadelphia, 8(4):October 1997
- Keye WR, Jr. Office Gynecology and Diagnostic Practice. In Scott J, DeSaia P, Hammond C, Spellacy W (eds):
Danforth's Obstetrics and Gynecology, 8th Edition. Lippincott-Raven, Philadelphia, pp 517-530, 1998
- Keye WR, Jr. Premenstrual Syndrome. In Koehler Carpenter SE, Rock JA (eds): Pediatric and Adolescent Gynecology, 2nd Edition. Lippincott-Raven, Philadelphia, pp 242-52, 2000
- Keye WR, Jr. Route of Administration and Clinical Efficacy of Gonadotropins. In Filicori M (ed): Endocrine Basis of Reproductive Function. Monduzzi Editore, Bologna, Italy, pp 375-82, 2000.
- Keye WR, Jr. Infertility: Is there a Role for the Surgeon. In Pitkin, RM, Scott JR, (eds): Clinical Obstetrics and Gynecology. Lippincott Williams & Wilkins, Inc., Philadelphia, pp 929-41,2000.
- Keye WR, Jr. Premenstrual Syndrome (PMS). In Adashi Eli Y (ed): Encyclopedia of Endocrinology and Endocrine Diseases. Academic Press, San Diego, California. (Submitted 9/02).
- Keye WR Jr. Office Gynecology. In Scott J, Gibbs R, Karlan B, Haney A (eds): Danforth’s Obstetrics and Gynecology, 9th Edition. Lippincott Williams & Wilkins, Philadelphia, pp 477-496, 2003.
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